Wilmer Alexander, Jr. and The Dukes, also known as "Wilmer and the Dukes", were a popular American soul music ensemble in the 1960s. They were known for their fusion of R&B, soul, and rock music, with a unique blend of saxophone and guitar creating their signature sound. The band, led by frontman Wilmer Alexander, Jr., was especially recognized for their live performances and their influential single, "Give Me One More Chance". Their impact on the soul music genre and their contribution to the music scene of Rochester, New York remains significant.