The Johnny Otis Show was an American R&B and rock group, fronted by singer, multi-instrumentalist, and songwriter Johnny Otis. The group, active primarily in the 1950s and 1960s, was known for its fusion of R&B, blues, and early rock and roll, with Otis often adopting the dual roles of bandleader and talent scout. They were influential in the evolution of R&B music, with significant works including "Willie and the Hand Jive" and "Harlem Nocturne." The band was also notable for fostering the careers of several noteworthy artists, such as Etta James and Big Mama Thornton.