Nino Tempo and 5th Ave. Sax is an American musical ensemble led by Nino Tempo, a celebrated saxophonist and actor. Known for their distinctive blend of pop, jazz, and rhythm and blues, the band's diverse style reflects Tempo's musical influences and extensive performance experience. Their most significant contribution to music history is the hit single "Sister James," which peaked at number 21 on the Billboard Hot 100 in 1973. Nino Tempo's virtuosic saxophone playing, characterized by intricate improvisations and vibrant tonal colors, is a defining feature of the band's sound.