The U.S. Males were a 1960s pop-rock band from Columbus, Ohio. They are best known for their single "Open Up Your Heart," a blend of melodic pop and garage rock that was a regional hit in the Midwest. The band's distinctive sound was characterized by rhythm guitar, keyboards, and harmony vocals, with a style influenced by British Invasion groups and American pop of the era. Despite their brief tenure, the U.S. Males had a significant local impact and represent a unique chapter in the history of Ohio's 1960s music scene.